With the exception of the external sites listed at the bottom, this page is an archive of federal resources that may not be available in their complete form from their primary source.
Federal Guidelines and Resources
Posted materials were downloaded or archived from Department of Health and Human Services websites on or before Jan. 30, 2025.
HIV Treatment Guidelines
PrEP and PEP
Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update
Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update Clinical Providers’ Supplement
Clinical Guidance for PEP (Post-Exposure Prophylaxis) (web.archive.org)
Updated Guidelines for Antiretroviral Postexposure Prophylaxis After Sexual, Injection Drug Use, or Other Nonoccupational Exposure to HIV— United States, 2016
STI Resources
Sexually Transmitted Infections Treatment Guidelines, 2021
CDC Clinical Guideline on the Use of Doxycycline Postexposure Prophylaxis for Bacterial Sexually Transmitted Infection Prevention, United States, 2024 (web.archive.org)
National Curricula
Posted materials were archived on or before Jan. 31, 2025.
HIV (web.archive.org)
PrEP (web.archive.org)
STD (web.archive.org)
TargetHIV (web.archive.org)
Technical assistance for Ryan White-funded agencies as archived on Jan. 24, 2025
HIV and STD Guideline, Resources & Data Repositories (External)
Sources for additional downloaded or archived documents or HIV-related guidelines
American Sexually Transmitted Diseases Association
National Network of STD Clinical Prevention Training Centers
New York State Department of Health AIDS Institute